The Spider-Man actor is the proud father of two children, daughter Ruby Sweetheart and son Otis Tobias, whom he shares with his ex-wife, Jennifer Meyer. After meeting in 2003, the former couple welcomed their firstborn, Ruby, in November 2006. Before tying the knot in 2007, Maguire appeared on The Late Show with David Letterman, sharing how fatherhood had transformed his life. “It’s a very dramatic change,” he said. “My whole life is in transition now with friendships and where I’m gonna live, you know, just your whole perspective.” He continued, “It’s great. She’s so adorable. She’s just a smiley, little, beautiful thing.”

Maguire and Meyer welcomed their second child, Otis, in May 2009. The Babylon actor shared on the Ellen DeGeneres Show six months after Otis’s birth that Ruby “just adores” her little brother. After nine years of marriage, Meyer announced their separation in 2016, stating that they would continue to co-parent. “After much soul-searching and consideration, we have made the decision to separate as a couple,” Maguire and Meyer said in a joint statement shared. “As devoted parents, our first priority remains raising our children together with enduring love, respect, and friendship.